Lactate peaks generated during high-intensity exercise provide neurobiological benefits to the brain through lactate-mediated neurotransmitter synthesis, including glutamate (the major excitatory neurotransmitter) and norepinephrine precursors, as demonstrated in human and animal studies.
causalpending
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Unidentified Speaker — Low-intensity & high-intensity cardiovascular training for … [6MVSUuMkELQ]Evidence Quote
“lactate also is is it's it's important for neurotransmitter synthesis you're you're um making glutamate the major excitatory neurotransmitter of the brain it's it's important for making precursors to that norepinephrine I mean these are all been shown in human studies also animal studies”
Source
Low-intensity & high-intensity cardiovascular training for longevity | Rhonda Patrick & Peter Attia— Peter Attia MDCreated: 8/12/2026, 2:27:11 AM
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