Bremelanotide (PT-141, Vylesi) is FDA-approved only for hypoactive sexual desire disorder in females despite working equally well in males, and it works by activating α-MSH and melanocortin receptors in the limbic system to enhance sexual arousal and spontaneous erections.
factualpending
Speaker
Dr. Kyle GilletteEvidence Quote
“bremelanotide this one uh also known as violisi is indicated for hypoactive sexual disorder whatever that is so that's obviously a very relative thing hypoactive hypoactive sexual disorder and oddly enough um it's only indicated in females although for sure it works on both females and males”
Source
Complete Guide to Peptides for Fat Loss, Muscle Building & Longevity | Dr. Kyle Gillett MD— Thomas DeLauerCreated: 8/13/2026, 4:51:25 AM
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