The melanocortin system links light exposure (UVB sunlight to eyes or skin) through the hypothalamus and pituitary to release of melanocyte-stimulating hormone, causing skin pigmentation while in parallel stimulating dopamine release; this conserved system explains why people and animals feel better, have more energy/libido, and (in animals) darken pelage and breed when sunlight increases in spring.

causalpending

Speaker

Andrew Huberman

Evidence Quote

This is the consequence of sunlight activating the melanocortico system. And by the way, this system is very active in other animals as well.

Source

Benefits & Risks of Peptide Therapeutics for Physical & Mental HealthAndrew Huberman
Created: 6/18/2026, 1:57:48 PM

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