The opioid pleasure system (liking) is smaller in brain extent, harder to trigger, but can be satiated; it is the basis of addiction because it operates differently from the wanting system.

definitionpending

Speaker

Richard Cytowic

Evidence Quote

“On the other hand, the opioid system is smaller in its expanse in the brain is harder to trigger. We can satiate and this is the basis of addictions, really.”

Source

Your brain wasn't built to hold this much information | Richard Cytowic— Big Think
Created: 8/12/2026, 6:39:44 PM

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