Glucose activates two mitochondrial enzymes (AMP kinase and HADH) that increase mitochondrial beta-oxidation and fuel burning, and AMP kinase is a primary signal for generating new mitochondria; fructose inhibits three mitochondrial enzymes (AMP kinase, ACAD-L, and CPT-1A), blocking fatty acid beta-oxidation and mitochondrial biogenesis
causalpending
Speaker
Robert LustigEvidence Quote
“glucose activated two enzymes that improved...mitochondrial beta oxidation...fructose inhibits three mitochondrial enzymes”
Source
The Subcellular Processes That Belie All Chronic Disease. The Hateful (or Grateful) Eight #lustig— Emery PharmaCreated: 8/10/2026, 10:44:48 PM
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