Substantia is a natural SARM-like compound under investigation, but its tissue selectivity profile is poorly understood ('terrifying'), making caution appropriate until more data emerges.
factualpending
Speaker
Dr. Kyle GilletteEvidence Quote
“substantia is one of them that's probably a naturalist arm we just don't know which tissues it's active in which is kind of terrifying”
Source
Complete Guide to Peptides for Fat Loss, Muscle Building & Longevity | Dr. Kyle Gillett MD— Thomas DeLauerCreated: 8/13/2026, 4:51:25 AM
My Notes
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