AMP kinase is critical for triggering autophagy; when AMP kinase is not working, autophagy stops, and fructose binds to the gamma subunit of AMP kinase causing non-competitive inhibition, thereby shutting down autophagy and leading to cellular dysfunction
causalpending
Speaker
Robert LustigEvidence Quote
“amp kinase...when it's working you get autophagy when it's not working autophagy stops...fructose...sits in the gamma subunit and causes non-competitive inhibition so autophagy stops”
Source
The Subcellular Processes That Belie All Chronic Disease. The Hateful (or Grateful) Eight #lustig— Emery PharmaCreated: 8/10/2026, 10:44:48 PM
My Notes
Loading notes...