Creatine may inhibit myostatin (a negative regulator of muscle growth), has neurological benefits, may affect fertility, and is used clinically in women at doses of 10+ grams to treat depression, making it one of the most broadly beneficial natural compounds beyond its well-known muscle and performance effects.
factualpending
Evidence Quote
“it's one of the only natural compounds that may inhibit myostat in to so it has that upside um and it's like all the things it does from a neurological standpoint perhaps fertility it's even used for depression now in women at like 10 plus grams or something which is crazy so a lot of use cases are coming out”
Source
How to sustainably lose fat while maintaining muscle | Peter Attia and Derek MPMD— Peter Attia MDCreated: 8/12/2026, 6:11:32 PM
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