What this covers
We used Tixel for my face and neck, and the Lutronic Ultra laser for my scalp.
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Brian Johnson demonstrates exosome therapy combined with Tixel thermomechanical ablation as his preferred anti-aging skin treatment, showing the protocol, mechanism, and comparative effectiveness versus alternatives like PRP and microneedling.
- Tixel creates microchannels in skin (100-1000 micrometers deep) that enable exosome absorption more effectively than traditional methods
- Exosomes derived from bone marrow and umbilical cord stem cells can halve recovery time while working on all skin types
- Johnson rates Tixel as the most effective therapy tested over 3 years of systematic anti-aging protocols
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Tixel therapy uses thermomechanical ablation with titanium spikes set at depths between 100 and 1,000 micrometers to create channels in skin for efficient exosome absorption
“we do this tixel therapy which is thermome mechanical oblation it opens up channels in the skin for the exosomes to be absorbed much more efficient effectively”
Using the Zimmer Chilla cooling device during Tixel treatment reduces pain by blowing cold air at -10 to -20°C on the skin
“you can use the Zim Chilla which we've got here to cool the skin down to - 10us 20° uh cold air blowing on it and that provides the pain reduction”
Tixel requires no anesthetic, making it more scalable to large body surface areas in a single session because topical anesthetics have overdose risks
“you don't need anesthetic so that's another reason why it's more SC ailable to the whole body CU you can only do so much topical anesthetic normally and Li Decay otherwise you get overdose it's very dangerous so in theory it is quite slow but you can do large body surface areas in a single session”
Tixel heats skin to 400°C during treatment, creating a sensation like a hot sear but with high pain-to-benefit ratio due to its brevity
“it Heats by 400° C... feels like you're getting a hot sear on your skin but it's very quick the pain to benefit ratio is very high”
Exosomes can halve recovery time compared to other treatments like PRP when used with Tixel
“exome me and camel stem exomes typically they can half the recovery time as well which is nice”
Tixel therapy affects the basal dermal layers because penetration depth of 100-1,000 micrometers goes through the epidermis (approximately 100 micrometers deep) into deeper skin structures
“you know goes through the epidermis which is around 100 micr deep so you're going to affect like the base dermal layers which is important”
Tixel creates open channels in skin that allow personalized topical drug delivery based on specific patient skin conditions and device settings
“with the drug delivery option as well you can um kind of personalize that to the patient skin condition CU it creates open channels depending on which settings you use”
Tixel works on all skin types more easily than lasers because it doesn't rely on light absorption and won't cause unintended hair removal
“it works on all skin types more easily there's no light involved and again you're not going to get the hair removal so with many lasers it's hard for guys to do it around jaw area CU you're going to remove beard”
A 1927 nanometer laser is used as a drug-assisted laser for hair treatment with exosomes, positioned as less invasive and more effective than PRP
“we also have exosomes for the hair so we're going to use a 1927 nanm laser same thing is drug assisted laser for the hair uh we're doing this instead of PRP so it's less invasive and hopefully more effective”
Tixel therapy is the most effective skin treatment Johnson has tested over his 3-year anti-aging protocol, compared to other therapies attempted
“we've tried a lot we think tixel is probably the most effective therapy we've done on the skin”
The exosomes being used contain 10 billion exosomes per vial with a hybrid cocktail of GMP-grade human bone marrow stem cells and human umbilical cord stem cells including MDX antiaging exosomes
“we're going to use a 1927 laser open up the channels for the drug delivery and then deliver the exosomes which are made of yeah with a combination uh 10 billion exomes per vile he a antiage MDX exomes and it's a hybrid cocktail GMP grade a mix of human bone marrow stem cells and human umbilical cord stem cells”
Treatment frequency with Tixel depends on recovery capacity, ranging from 4 weeks to 8 weeks when using high settings and exosomes
“depends on your recovery we are using exom so it could be 4 weeks you know in the manual they do say if you're going on very high settings then more in the you know 4 to 8 weeks kind of range”
Johnson had severe sun damage to his skin including UV damage, browning, and redness because he was frequently in the sun as a child and never wore sunscreen
“when we started blueprint three years ago I had really bad skin damage I was in the sun all the time as a kid I never wore sunscreen”
The protocol requires facial skin to be very dry before Tixel application for maximum efficacy
“The protocol is getting my face really really dry so I just wash my face so I'm just drying it off it's more efficacious when it's dry”
Brian Johnson has been systematically trying to slow his aging speed using data and science for the past 3 years
“for the past 3 years I've been trying to slow my speed of Aging as much as possible using data and science”
Johnson has tried multiple hair growth interventions including liquid minoxidil, laser dialos for a hair cap, and PRP before moving to exosomes
“we're trying to increase hair growth and we've been trying things like liquid manoil and uh laser dialos for a hair cap and PRP we're trying to move on to better stuff and now we're trying exosomes”
Johnson is genetically predisposed to baldness but has maintained hair, which he attributes to his anti-aging interventions
“genetically I should be bald still have hair which is great”