The strongest evidence for psilocybin's therapeutic use is for cancer-related depression, cancer-related anxiety, and treatment-resistant depression; there is moderate evidence for alcohol use disorder, dependence, and tobacco addiction; and weaker evidence for obsessive compulsive disorder, cluster headaches, migraines, and demoralization due to AIDS diagnosis.
factualpending
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Andrew HubermanEvidence Quote
“the most evidence for positive therapeutic outcomes...is for cancer-related depression, cancer-related anxiety, and treatment resistant depression...some evidence for...alcohol use disorder, and dependence, and tobacco addiction...the least amount of evidence...obsessive compulsive disorder, cluster headaches and migraines, and demoralization due to AIDS diagnosis”
Created: 8/12/2026, 6:37:08 PM
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