Approximately 90% of the serotonin in the brain and body is manufactured in the gut, but the serotonin in the brain is manufactured separately from gut serotonin by specific neurons in the brain, contradicting the popular belief that brain serotonin comes from gut serotonin.
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Andrew HubermanEvidence Quote
“about 90% of the serotonin in your brain and body is manufactured in your gut. However, contrary to popular belief, the serotonin in your brain is not manufactured from the serotonin in your gut [13:36]”
Created: 8/12/2026, 6:37:08 PM
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