The concentration of psilocybin in different strains of magic mushrooms varies tremendously, ranging anywhere from 0.5% to 2% of dry weight, meaning that someone taking the same gram amount of mushrooms from different batches could be ingesting anywhere from 5mg to 20mg of psilocybin depending on strain and batch variability.

factualpending

Speaker

Andrew Huberman

Evidence Quote

the concentration of psilocybin in different strains of mushrooms and in different batches...can vary tremendously from batch to batch...anywhere from 1/2% all the way up to 2%

Source

How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its RisksAndrew Huberman
Created: 8/12/2026, 6:37:08 PM

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