Claims

Building the periodic table experiment with astatine represents a 'quantity that maximizes the amount of paperwork you're going to have to face' because a smaller amount might be coverable (charred walls, radioactivity, discretely cleanable with 20% time), but a liter would demolish the building, while a larger amount would leave no one to submit paperwork.

Munroe received concerning 'What If' submissions including one from someone with apparent nuclear weapons access asking about nuclear physics, and another from a medical doctor asking about the effects of a toxin on patient receptors at a specific dose, suggesting potential misuse scenarios.

The correct response to row 4 hazards is to run away very quickly and stop building rows, rather than proceeding to rows 5-7.